Unlocking the Power of the Genome &nbsp;

Illumina


Senior Scientist - Analytical Core

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As a Senior Scientist in Illumina's Analytical Core, you will provide advanced analytical expertise across R&D and product development. This role involves applying LC-MS capabilities to support discovery, development, and investigation efforts, with a strong focus on oligonucleotide analyses. You will design and execute analytical strategies, develop LC-MS methods, interpret complex datasets, and partner with cross-functional teams to deliver actionable insights, contributing to innovation in genomic technology.

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What if the work you did every day could impact the lives of people you know? Or all of humanity?At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.<h3 class="text-xl md:text-2xl font-bold mt-8 mb-3 text-gray-800">Position Summary</h3>As a Senior Scientist within Illumina’s Analytical Core, you will join a centralized, high-impact team providing advanced analytical expertise across R&D and product development. The Analytical Core partners broadly across the organization to solve complex scientific problems, deliver rapid analytical insight, and enable innovation across Illumina’s technologies. This role is ideal for an experienced analytical chemist with deep LC-MS expertise, including experience with both QToF and QQQ systems. Familiarity with oligonucleotide analyses is strongly preferred.<h3 class="text-xl md:text-2xl font-bold mt-8 mb-3 text-gray-800">The Role</h3>As a Senior Scientist in the Analytical Core, you will serve as a hands-on technical leader, applying advanced LC-MS capabilities to support discovery, development, and investigation efforts across Illumina.Working in a fast-paced, highly collaborative environment, you will design and execute analytical strategies, develop and optimize LC-MS methods, and interpret complex datasets for a wide range of analytes, including small molecules and oligonucleotides. You will routinely partner with cross-functional teams, delivering clear, actionable insights that support innovation while upholding Illumina’s value of Innovate with Purpose.This position is suited to a PhD-level scientist with postdoctoral and/or industry experience who is comfortable operating independently while contributing to a shared, service-oriented scientific mission.<h3 class="text-xl md:text-2xl font-bold mt-8 mb-3 text-gray-800">Why You</h3>You bring a PhD in Analytical Chemistry, Chemistry, Biochemistry, or a related discipline, along with substantial hands-on experience in LC-MS, ideally including QQQ instrumentation. You have direct experience with oligonucleotide analysis by LC-MS, including method development, characterization, and data interpretation. You are comfortable working with deconvolution-focused data analysis tools such as Agilent BioConfirm, or equivalent software used for oligo identity, purity, and modification analysis.You are confident designing experiments, troubleshooting complex analytical systems, and translating data into meaningful scientific insight. Curious, organized, and accountable, you thrive in environments that require prioritization across multiple projects while maintaining a high bar for scientific rigor.Your strong communication skills and collaborative mindset allow you to work effectively with scientists and engineers from diverse backgrounds, contributing to a strong culture of collective achievement.<h3 class="text-xl md:text-2xl font-bold mt-8 mb-3 text-gray-800">Key Responsibilities:</h3><ul class="list-disc list-inside my-5 pl-5 space-y-2 text-gray-700"><li class="leading-relaxed">Develop, optimize, and execute LC-MS -based experiments for small molecule & biomolecule discovery, identification, and quantitation.</li><li class="leading-relaxed">Perform oligonucleotide analysis by LC-MS, including identity confirmation, impurity profiling, and quantitative or semi-quantitative assessments. Apply and interpret data using Agilent BioConfirm or related software.</li><li class="leading-relaxed">Lead complex analytical investigations independently, from triaging priority to experimental design through data interpretation and presentation.</li><li class="leading-relaxed">Operate, maintain, and troubleshoot advanced analytical instrumentation, including LC-QQQ, LC-QTOF, and HPLC systems.</li><li class="leading-relaxed">Analyze and interpret complex datasets, translating results into clear, actionable conclusions for project teams.</li><li class="leading-relaxed">Partner closely with cross-functional collaborators to define analytical strategies and deliver high-quality, timely results.</li><li class="leading-relaxed">Contribute to Core laboratory operations, including documentation, best practices, training, and continuous improvement initiatives.</li><li class="leading-relaxed">Serve as a subject-matter expert in LC-MS analysis, providing technical guidance and mentorship as appropriate</li><li class="leading-relaxed">Experience with other analytical techniques, such as ICP-MS, GC-MS, and NMR, preferred.</li></ul><h3 class="text-xl md:text-2xl font-bold mt-8 mb-3 text-gray-800">Experience/Education:</h3><ul class="list-disc list-inside my-5 pl-5 space-y-2 text-gray-700"><li class="leading-relaxed">Typically requires a minimum of 5+ years of related experience with a Bachelor’s / Master's degree; PhD with 1-2+ years experience highly preferred.</li></ul>The estimated base salary range for the Senior Scientist - Analytical Core role based in the United States of America is: $98,400 - $147,600. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. Compensation decisions are dependent on several factors including, but not limited to, an’s qualifications, location where the role is to be performed, internal equity, and alignment with market data. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact accommodations@illumina.com. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.

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<h4 class="text-lg md:text-xl font-semibold mt-6 mb-2 text-gray-800">Privacy Notice</h4>This website uses cookies to improve your web experience. By using the site, you agree to the use of cookies.DismissWhy CodaCoda is a global growth engine for commerce. We bring together powerful capabilities that connect people, digital products, and payments through our suite of trusted digital monetization and distribution solutions.We recently acquired Recharge, Europe’s leading prepaid payments and digital gift card business, bringing both companies together into one organisation with broader reach, deeper capabilities across B2B and B2C commerce and a stronger global footprint.Today, we stand as a team of more than 600 people, representing 57 nationalities across 23 locations. We are headquartered in Singapore with offices in Amsterdam, Dubai, Shanghai and other hubs across Southeast Asia.Our B2B business works with publishers and brands to support growth across markets. 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Our toolbox includes JSON and GRPC, multiple data storage integrations, queues, OpenTelemetry, and more.But what truly defines us? It's our incredible team. We hire top talent and give them the freedom to push Coda's technology and products to exciting new levels. We believe that genius can strike anywhere, so we promote ownership and cultivate a servant leadership culture that lets engineers take the reins on features.We are looking for experienced Infrastructure Operations Engineers to join our team. Candidates should have at least 3 years of relevant experience in infrastructure operations or a similar role.Your final level will be determined based on your experience and performance during the interview process.<h3 class="text-xl md:text-2xl font-bold mt-8 mb-3 text-gray-800">Responsibilities</h3><ul class="list-disc list-inside my-5 pl-5 space-y-2 text-gray-700"><li class="leading-relaxed">Design and implement scalable, secure, and highly available cloud infrastructure for high-traffic, geographically distributed workloads</li><li class="leading-relaxed">Automate infrastructure creation and management using Terraform or other IaC tools</li><li class="leading-relaxed">Optimize cloud infrastructure costs while maintaining performance and reliability</li><li class="leading-relaxed">Design and implement disaster recovery and backup solutions</li><li class="leading-relaxed">Implement and maintain CI/CD pipelines for infrastructure deployment</li><li class="leading-relaxed">Proactively identify and rectify risks within infrastructure, networks and security</li><li class="leading-relaxed">Continuously improve existing architecture, systems and processes</li><li class="leading-relaxed">Mentor junior engineers and contribute to technical decision-making</li><li class="leading-relaxed">Participate in on-call rotation for production support</li><li class="leading-relaxed">Troubleshoot systems and solve problems across platform and application domains</li></ul><h3 class="text-xl md:text-2xl font-bold mt-8 mb-3 text-gray-800">Required Skills & Experience</h3><ul class="list-disc list-inside my-5 pl-5 space-y-2 text-gray-700"><li class="leading-relaxed">2+ years hands-on experience with AWS services including:</li><li class="leading-relaxed">EC2, ECS, Lambda, API Gateway</li><li class="leading-relaxed">RDS, DynamoDB, OpenSearch, ElastiCache</li><li class="leading-relaxed">VPC, Route53, CloudFront, SQS, SNS</li><li class="leading-relaxed">IAM, KMS, Security Groups, WAF</li><li class="leading-relaxed">CloudWatch, CloudTrail, Config, SSO</li><li class="leading-relaxed">1+ years of experience with Terraform or similar infrastructure as code tools (CloudFormation, Serverless Framework, Pulumi)</li><li class="leading-relaxed">Strong Linux/Unix administration skills</li><li class="leading-relaxed">Strong understanding of networking concepts and security best practices</li><li class="leading-relaxed">Understanding of cryptography concepts including:</li><li class="leading-relaxed">Public key infrastructure (PKI) and asymmetric encryption</li><li class="leading-relaxed">TLS certificate management and lifecycleEnd-to-end encryption</li><li class="leading-relaxed">Envelope encryption and key management systems</li><li class="leading-relaxed">Proficiency in scripting languages (Python, Bash, JavaScript)</li><li class="leading-relaxed">Experience with containerization (Docker) and orchestration (ECS, Kubernetes)</li><li class="leading-relaxed">Experience with monitoring and observability tools (ELK, Grafana, Prometheus, OpenTelemetry)</li><li class="leading-relaxed">Experience with configuration management tools (Ansible, Salt, Puppet, Chef)</li></ul><h3 class="text-xl md:text-2xl font-bold mt-8 mb-3 text-gray-800">Preferred Qualifications</h3><ul class="list-disc list-inside my-5 pl-5 space-y-2 text-gray-700"><li class="leading-relaxed">Experience with high-traffic, distributed systems</li><li class="leading-relaxed">Knowledge of payment industry security standards (PCI-DSS)</li><li class="leading-relaxed">Experience with edge cloud services (Cloudflare, Akami)</li><li class="leading-relaxed">Contributions to open-source projects</li><li class="leading-relaxed">Experience with performance tuning and optimization</li><li class="leading-relaxed">Knowledge of financial technology domain</li><li class="leading-relaxed">Great communication skills</li></ul>We are proud to be an equal opportunity employer, embracing the unique qualities of every individual, regardless of gender, race, age, religion, disability, or other local protected classes. 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This assessment gives us an idea of your C++ skills- Companies that evaluate this skillset in interviews: Rockstar Games, Ubisoft, Mayhem Studios, etc.- 10 Multiple Choice questions- Average time to complete: 7 to 10 minutes

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