The Head of Quantitative Research & Analysis role involves leading a quantitative investment research team to identify, model, and develop successful trading strategies across centralized and decentralized crypto exchanges and options markets. Key responsibilities include designing high-frequency trading strategies, collaborating with the development team, conducting backtesting, developing analytical tools, managing trading risk, executing trades, monitoring auto trading strategies, and communicating market updates. The role requires leading a team and contributing to the growth of digital asset trading.