Bioinformatics Scientist – Mortality Risk Modeling

6 Minutes ago • 4 Years + • Research Development • $133,000 PA - $236,000 PA

Job Summary

Job Description

Ethos is seeking a Bioinformatics Scientist for its actuarial and underwriting innovation team. This role involves redefining mortality risk assessment by applying bioinformatics, survival analysis, and machine learning to novel health and behavioral data. The scientist will lead research and model development, integrating clinical biomarkers, medical history, and emerging data sources to create next-generation predictive frameworks. Collaborating with actuaries, underwriters, data scientists, and engineers, the goal is to design interpretable, production-ready models that enhance underwriting fairness and accuracy, ultimately expanding affordable life insurance access.
Must have:
  • Design and execute studies using novel data to improve mortality risk prediction
  • Develop and validate ML and statistical models for mortality scoring
  • Partner with Data Science and Engineering to bring models into production
  • Collaborate with Actuarial and Underwriting teams to align on validation and impact
  • Contribute to the methodology and roadmap of a modern, scalable mortality modeling system
  • Experience working with medical ontologies, terminologies, or clinical data models
  • Applied bioinformatics or statistical modeling techniques to real-world health, biometric, or survival datasets
  • Fluent in Python or R, and experience with machine learning libraries or survival analysis frameworks
  • Thrive in cross-functional settings and communicate technical findings clearly
  • MS or PhD in Bioinformatics, Statistics, Biostatistics, Applied Mathematics, Data Science, or similar
  • 4+ years of experience in applied statistical modeling or machine learning
  • Strong proficiency in Python or R and relevant libraries
Good to have:
  • Experience in survival modeling, biomarker analysis, or health risk scoring

Job Details

About Ethos

Ethos was built to make it faster and easier to get life insurance for the next million families. Our approach blends industry expertise, technology, and the human touch to find you the right policy to protect your loved ones.

We leverage deep technology and data science to streamline the life insurance process, making it more accessible and convenient. Using predictive analytics, we are able to transform a traditionally multi-week process into a modern digital experience for our users that can take just minutes! We’ve issued billions in coverage each month and eliminated the traditional barriers, ushering the industry into the modern age. Our full-stack technology platform is the backbone of family financial health.

We make getting life insurance easier, faster and better for everyone.

Our investors include General Catalyst, Sequoia Capital, Accel Partners, Google Ventures, SoftBank, and the investment vehicles of Jay-Z, Kevin Durant, Robert Downey Jr and others. This year, we were named on CB Insights' Global Insurtech 50 list and BuiltIn's Top 100 Midsize Companies in San Francisco. We are scaling quickly and looking for passionate people to protect the next million families!

About the Role:

Ethos is looking for a bioinformatics scientist to join our actuarial and underwriting innovation team. In this role, you will help redefine how life insurers assess mortality risk by applying bioinformatics, survival analysis, and machine learning to novel health and behavioral data. You’ll lead research and model development efforts that go beyond traditional actuarial inputs — integrating signals from clinical biomarkers, medical history, and emerging data sources to create next-generation predictive frameworks.

This is a unique opportunity to bring your background in bioinformatics, computational health, or applied statistics into a space that’s ripe for reinvention. You’ll collaborate closely with actuaries, underwriters, data scientists, and engineers to design interpretable, production-ready models that improve both underwriting fairness and accuracy. Ultimately, helping us expand affordable life insurance access to more people.

If you're excited about applying scientific rigor to complex real-world risk problems, and want to help modernize an industry from the inside out, we’d love to hear from you.

Duties and Responsibilities:

  • Design and execute studies using novel data to improve mortality risk prediction.
  • Develop and validate ML and statistical models for mortality scoring.
  • Partner with Data Science and Engineering to bring models into production.
  • Collaborate with Actuarial and Underwriting teams to align on validation and impact.
  • Contribute to the methodology and roadmap of a modern, scalable mortality modeling system.

Qualifications and Skills:

  • You have experience working with medical ontologies, terminologies, or clinical data models that support robust analytical workflows. (e.g., ICD, SNOMED, LOINC, OMOP CDM, etc.)
  • You’ve applied bioinformatics or statistical modeling techniques to real-world health, biometric, or survival datasets and know how to balance rigor with practicality.
  • You’re fluent in tools like Python or R, and have experience with machine learning libraries or survival analysis frameworks.
  • You thrive in cross-functional settings, working alongside actuaries, underwriters, engineers, and product teams and can communicate technical findings clearly to diverse audiences.
  • You're excited to bring a scientific mindset to an industry ripe for reinvention and are ready to challenge assumptions while building credible, production-ready tools.
  • MS or PhD in Bioinformatics, Statistics, Biostatistics, Applied Mathematics, Data Science, or similar.
  • 4+ years of experience in applied statistical modeling or machine learning.
  • Strong proficiency in Python or R and relevant libraries.
  • Experience in survival modeling, biomarker analysis, or health risk scoring preferred.
  • Excellent communication skills and ability to write clearly for technical audiences.

The US national base salary range for this full-time position is $133,000 - $236,000. Our salary ranges are determined by role, level, and location. The range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position across all US locations. Within the range, individual pay is determined by work location and additional factors, including job-related skills, experience, and relevant education or training.

Please note that the compensation details listed in US role postings reflect the base salary only, and do not include applicable bonus, equity, or benefits.

You can find further details of our US benefits at https://www.ethoslife.com/careers/

Don’t meet every single requirement? If you’re excited about this role but your past experience doesn’t align perfectly with every qualification in the job description, we encourage you to apply anyway. At Ethos we are dedicated to building a diverse, inclusive and authentic workplace.

We are an equal opportunity employer who values diversity and inclusion and look for applicants who understand, embrace and thrive in a multicultural world. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. Pursuant to the SF Fair Chance Ordinance, we will consider employment for qualified applicants with arrests and conviction records.

To learn more about what information we collect and how it may be used, please refer to our California Candidate Privacy Notice

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About The Company

Ethos was built to make it faster and easier to get term life insurance. Our approach blends industry expertise, technology, and the human touch to find you the right policy to protect your loved ones. Using predictive analytics, we are able to transform a traditionally 15-week process into a modern digital experience for our users. Ethos has raised over $400 million from Sequoia Capital, SoftBank Vision Fund 2, Accel, and Google Ventures (GV). We are scaling quickly and looking for passionate people to join us in our mission to protect the next million families!

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