Computational Biology - Postdoctoral Researcher

3 Months ago • All levels • Research Development

Job Summary

Job Description

This is a two-year Postdoctoral appointment with the possibility of extension to a maximum of three years. The selected candidate will conduct research in computational microbiology, focusing on microbial ecology and community engineering, developing models of metabolism in bacteria and algae, and investigating symbiotic interactions. The role involves designing experiments, analyzing data, collaborating with biologists, developing computational tools, and publishing research. The position requires full-time on-site presence due to the nature of the work. This role is designed to promote cutting-edge science, requiring interactions with experimental biologists on a day-to-day basis.
Must have:
  • PhD in related field.
  • Understanding of microbial physiology and systems biology.
  • Experience in mathematical modeling.
  • Experience in bioinformatics and computational analyses.
  • Familiarity with system-level modeling methods.
  • Effective communication skills.
Good to have:
  • Familiarity with programming for parallel computing.
  • Experience using tools of linear programming and operations research.
Perks:
  • Flexible Benefits Package
  • 401(k)
  • Relocation Assistance
  • Education Reimbursement Program
  • Flexible schedules

Job Details

Company Description

Join us and make YOUR mark on the World!

Are you interested in joining some of the brightest talent in the world to strengthen the United States’ security? Come join Lawrence Livermore National Laboratory (LLNL) where our employees apply their expertise to create solutions for BIG ideas that make our world a better place.

We are dedicated to fostering a culture that values individuals, talents, partnerships, ideas, experiences, and different perspectives, recognizing their importance to the continued success of the Laboratory’s mission.

Pay Range

$9,907 monthly

Job Description

Note: This is a two-year Postdoctoral appointment with the possibility of extension to a maximum of three years.

We have an opening for a Postdoctoral Researcher to conduct research in the areas of computational systems biology. This research will involve development and use of detailed system-level models of metabolism in microbial communities and development of novel constraint-based modeling methods.  These models and tools will be used to examine the biochemical mechanisms of intercellular interactions. This research could involve development of multiple types of models including genome-scale steady state models, reaction-transport dynamic models, and some ML models.  Some of the modeling efforts involve use of LLNL’s high-performance computing. The position is part of a larger project aiming to develop comprehensive understanding of the systems level resource allocation consequences of microscale symbioses between microbes and bioenergy and bioproduct relevant crops (https://bio-sfa.llnl.gov). The purpose of this appointment is to promote cutting-edge science and requires day-to-day interactions with experimental biologists.  This position is in the Biochemical and Biophysical Systems group of the Biosciences and Biotechnology Division. 

This position requires full-time on-site presence due to the nature of the work.

You will 

  • Conduct research in computational microbiology in the areas of microbial ecology and microbial community engineering.
  • Develop genome-scale models of metabolism in bacteria and algae.
  • Develop spatially multiscale dynamic reaction and transport models of biophysical systems.
  • Investigate the system-level underpinnings of processes involved in symbiotic interactions between algae and bacteria in co-cultured communities. 
  • Examining interaction between microbes and the surrounding medium using methods such as dynamic flux balance analysis and flux sampling.
  • Contribute to the conception, design and execution of experiments and in silico analyses to address defined problems.
  • Communicate with experimental biologists for systems biology studies.
  • Develop new computational tools for high performance computing studies.
  • Work in a collaborative multidisciplinary team environment to accomplish goals.
  • Publish research in peer-reviewed journals and present research at conferences.
  • Perform other duties as assigned.

Qualifications

  • Recent PhD in microbiology, bioengineering, computer science, chemistry/biochemistry, physics or related field.
  • Demonstrated understanding of the concepts of microbial physiology (particularly metabolism), systems biology and dynamics of multi-cellular communities.
  • Previous experience in mathematical modeling of networks.
  • Experience in bioinformatics and computational analyses.
  • Familiarity with system-level modeling methods like FBA and tools like COBRA.
  • Demonstrated effective communication skills through publication of journal articles and presentations at seminars and scientific meetings.
  • Demonstrated leadership skills with desire and ability to work in a collaborative, multidisciplinary team environment.  

Qualifications We Desire

  • Familiarity with programming for parallel computing.
  • Experience using tools of linear programming and operations research.

Additional Information

#LI-Onsite

Position Information

This is a Postdoctoral appointment with the possibility of extension to a maximum of three years, open to those who have been awarded a PhD at time of hire date.

Why Lawrence Livermore National Laboratory?

Security Clearance

None required.  However, if your assignment is longer than 179 days cumulatively within a calendar year, you must go through the Personal Identity Verification process.  This process includes completing an online background investigation form and receiving approval of the background check.  (This process does not apply to foreign nationals.) 

National Defense Authorization Act (NDAA)

The 2025 National Defense Authorization Act (NDAA), Section 3112, generally prohibits citizens of China, Russia, Iran and North Korea without dual US citizenship or legal permanent residence from accessing specific non-public areas of national security or nuclear weapons facilities.  The restrictions of NDAA Section 3112 apply to this position.  To be qualified for this position, Candidates must be eligible to access the Laboratory in compliance with Section 3112.

Pre-Employment Drug Test

External applicant(s) selected for this position must pass a post-offer, pre-employment drug test. This includes testing for use of marijuana as Federal Law applies to us as a Federal Contractor.

Wireless and Medical Devices

Per the Department of Energy (DOE), Lawrence Livermore National Laboratory must meet certain restrictions with the use and/or possession of mobile devices in Limited Areas. Depending on your job duties, you may be required to work in a Limited Area where you are not permitted to have a personal and/or laboratory mobile device in your possession.  This includes, but not limited to cell phones, tablets, fitness devices, wireless headphones, and other Bluetooth/wireless enabled devices.  

If you use a medical device, which pairs with a mobile device, you must still follow the rules concerning the mobile device in individual sections within Limited Areas.  Sensitive Compartmented Information Facilities require separate approval. Hearing aids without wireless capabilities or wireless that has been disabled are allowed in Limited Areas, Secure Space and Transit/Buffer Space within buildings.

How to identify fake job advertisements

Please be aware of recruitment scams where people or entities are misusing the name of Lawrence Livermore National Laboratory (LLNL) to post fake job advertisements. LLNL never extends an offer without a personal interview and will never charge a fee for joining our company. All current job openings are displayed on the Career Page under “Find Your Job” of our website. If you have encountered a job posting or have been approached with a job offer that you suspect may be fraudulent, we strongly recommend you do not respond.

To learn more about recruitment scams: https://www.llnl.gov/sites/www/files/2023-05/LLNL-Job-Fraud-Statement-Updated-4.26.23.pdf

Equal Employment Opportunity

We are an equal opportunity employer that is committed to providing all with a work environment free of discrimination and harassment. All qualified applicants will receive consideration for employment without regard to race, color, religion, marital status, national origin, ancestry, sex, sexual orientation, gender identity, disability, medical condition, pregnancy, protected veteran status, age, citizenship, or any other characteristic protected by applicable laws.

Reasonable Accommodation

Our goal is to create an accessible and inclusive experience for all candidates applying and interviewing at the Laboratory.  If you need a reasonable accommodation during the application or the recruiting process, please use our online form to submit a request. 

California Privacy Notice

The California Consumer Privacy Act (CCPA) grants privacy rights to all California residents. The law also entitles job applicants, employees, and non-employee workers to be notified of what personal information LLNL collects and for what purpose. The Employee Privacy Notice can be accessed here.

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