Senior Bioinformatics Software Engineer

26 Minutes ago • 3-6 Years • Software Development & Engineering • $126,800 PA - $190,200 PA

Job Summary

Job Description

Illumina is seeking a Sr. Bioinformatics Software Engineer to expand access to genomic technology and realize health equity. The role involves leading testing efforts for data analysis software, partnering with development teams, designing and implementing automated verification frameworks, and preparing test artifacts for product release. Responsibilities include developing and executing automated and unit tests, analyzing and reporting test results, participating in code and design reviews, and ensuring adherence to Software Development Life Cycle procedures. The engineer will collaborate with assay development teams, identify process improvements, and demonstrate curiosity, attention to detail, and analytical skills. The role requires customer focus, teamwork, self-management, and strong communication and troubleshooting abilities.
Must have:
  • 4+ years of experience in formal verification of software/systems in a regulated environment.
  • 6+ years of experience in software/system verification & validation.
  • Background in developing and maintaining Bioinformatics pipelines.
  • Experience with commercial cloud platforms (AWS, Azure, GCP).
  • Ability to develop automated scripts using Python, BASH.
  • Basic knowledge of Linux and CLI environment.
  • Skills in writing verification plans, protocols, and reports.
  • Understanding of Oncology, Molecular Biology, or Bioinformatics.
  • Ability to manage and mentor a small team.
Good to have:
  • Previous experience using Illumina's DRAGEN secondary analysis solution.
  • Skills with workflow languages like Nextflow, Snakemake, WDL.
Perks:
  • Access to genomics sequencing
  • Family planning benefits
  • Health/dental/vision insurance
  • Retirement benefits
  • Paid time off
  • Variable cash programs (bonus or commission)
  • Potential equity compensation

Job Details

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Responsibilities:

  • Work independently in cross-functional teams to lead the testing effort for data analysis software
  • Partner with software, bioinformatics developers and domain experts in designing, performing, and improving verification tests
  • Design and Implement automated software verification framework and scripts
  • Prepare necessary test artifacts required for formal software / product release
  • Develop and execute automated and unit tests
  • Carefully analyze and report test results
  • Participate in Code and Design Reviews
  • Ensure Software Development Life Cycle procedures are followed
  • Collaborate closely with assay development team and ensure they well trained on using the informatics software application(s)
  • Collaborate with peers to identify opportunities for process improvement
  • Be curious, detail oriented, and analytical, with a proven ability to learn quickly
  • Be customer-focused, team-oriented, and motivated, taking ownership of assigned tasks
  • Have proven ability to self-manage, as well as manage interdisciplinary relationships
  • Good verbal and written communication and troubleshooting skills

Requirements:

  • Typically requires a minimum of 5 years of related experience with a Bachelor’s degree; or 3 years and a Master’s degree; or a PhD without experience; or equivalent work experience. 
  • 4+ years of experience in formal verification of software or system in a regulated environment (ex. medical device etc.)
  • 6+ years of working experience with software or system verification & validation
  • Background in developing and maintaining Bioinformatics pipelines and workflow is a must.
  • Previous experience using Illumina's DRAGEN secondary analysis solution is a plus
  • Having good knowledge of running Bioinformatics workflows in any commercial cloud (AWS, Azure, GCP) is required
  • Prior skills with workflow languages like Nextflow, Snakemake, WDL etc.
  • Ability to develop automated scripts to large scale analysis using Python, BASH etc.
  • Basic knowledge of Linux and comfortable working with CLI environment
  • Proven skills for writing verification plan, protocol, report and all aspects of documentation required for formally releasing a product
  • Have an understanding of Oncology, Molecular Biology, Bioinformatics, or related field of biology along with software informatics application experience
  • Ability to manage and mentor small team
  • Proven ability to work with internal and external teams and interface with customers

.

#LI-HYBRID

The estimated base salary range for the Sr Bioinformatics Software Engineer role based in the United States of America is: $126,800 - $190,200. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. Compensation decisions are dependent on several factors including, but not limited to, an individual’s qualifications, location where the role is to be performed, internal equity, and alignment with market data. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.


We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact accommodations@illumina.com. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants.

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About The Company

At Illumina, our goal is to apply innovative technologies and revolutionary assays to the analysis of genetic variation and function, making studies possible that were not even imaginable just a few years ago. These studies will help make the realization of personalized medicine possible. With such rapid advances in technology taking place, it is mission critical to have solutions that are not only innovative, but flexible, scalable, and complete with industry-leading support and service. As a global company that places high value on collaborative interactions, rapid delivery of solutions, and prioritizing the needs of its customers, we strive to meet this challenge. Illumina’s innovative, array-based solutions for DNA, RNA, and protein analysis serve as tools for disease research, drug development, and the development of molecular tests in the clinic.



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