Senior Bioinformatics Software Engineer

2 Months ago • 3-6 Years • Software Development & Engineering • $126,800 PA - $190,200 PA

Job Summary

Job Description

Illumina is seeking a Sr. Bioinformatics Software Engineer to expand access to genomic technology and realize health equity. The role involves leading testing efforts for data analysis software, partnering with development teams, designing and implementing automated verification frameworks, and preparing test artifacts for product release. Responsibilities include developing and executing automated and unit tests, analyzing and reporting test results, participating in code and design reviews, and ensuring adherence to Software Development Life Cycle procedures. The engineer will collaborate with assay development teams, identify process improvements, and demonstrate curiosity, attention to detail, and analytical skills. The role requires customer focus, teamwork, self-management, and strong communication and troubleshooting abilities.
Must have:
  • 4+ years of experience in formal verification of software/systems in a regulated environment.
  • 6+ years of experience in software/system verification & validation.
  • Background in developing and maintaining Bioinformatics pipelines.
  • Experience with commercial cloud platforms (AWS, Azure, GCP).
  • Ability to develop automated scripts using Python, BASH.
  • Basic knowledge of Linux and CLI environment.
  • Skills in writing verification plans, protocols, and reports.
  • Understanding of Oncology, Molecular Biology, or Bioinformatics.
  • Ability to manage and mentor a small team.
Good to have:
  • Previous experience using Illumina's DRAGEN secondary analysis solution.
  • Skills with workflow languages like Nextflow, Snakemake, WDL.
Perks:
  • Access to genomics sequencing
  • Family planning benefits
  • Health/dental/vision insurance
  • Retirement benefits
  • Paid time off
  • Variable cash programs (bonus or commission)
  • Potential equity compensation

Job Details

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Responsibilities:

  • Work independently in cross-functional teams to lead the testing effort for data analysis software
  • Partner with software, bioinformatics developers and domain experts in designing, performing, and improving verification tests
  • Design and Implement automated software verification framework and scripts
  • Prepare necessary test artifacts required for formal software / product release
  • Develop and execute automated and unit tests
  • Carefully analyze and report test results
  • Participate in Code and Design Reviews
  • Ensure Software Development Life Cycle procedures are followed
  • Collaborate closely with assay development team and ensure they well trained on using the informatics software application(s)
  • Collaborate with peers to identify opportunities for process improvement
  • Be curious, detail oriented, and analytical, with a proven ability to learn quickly
  • Be customer-focused, team-oriented, and motivated, taking ownership of assigned tasks
  • Have proven ability to self-manage, as well as manage interdisciplinary relationships
  • Good verbal and written communication and troubleshooting skills

Requirements:

  • Typically requires a minimum of 5 years of related experience with a Bachelor’s degree; or 3 years and a Master’s degree; or a PhD without experience; or equivalent work experience. 
  • 4+ years of experience in formal verification of software or system in a regulated environment (ex. medical device etc.)
  • 6+ years of working experience with software or system verification & validation
  • Background in developing and maintaining Bioinformatics pipelines and workflow is a must.
  • Previous experience using Illumina's DRAGEN secondary analysis solution is a plus
  • Having good knowledge of running Bioinformatics workflows in any commercial cloud (AWS, Azure, GCP) is required
  • Prior skills with workflow languages like Nextflow, Snakemake, WDL etc.
  • Ability to develop automated scripts to large scale analysis using Python, BASH etc.
  • Basic knowledge of Linux and comfortable working with CLI environment
  • Proven skills for writing verification plan, protocol, report and all aspects of documentation required for formally releasing a product
  • Have an understanding of Oncology, Molecular Biology, Bioinformatics, or related field of biology along with software informatics application experience
  • Ability to manage and mentor small team
  • Proven ability to work with internal and external teams and interface with customers

.

#LI-HYBRID

The estimated base salary range for the Sr Bioinformatics Software Engineer role based in the United States of America is: $126,800 - $190,200. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. Compensation decisions are dependent on several factors including, but not limited to, an individual’s qualifications, location where the role is to be performed, internal equity, and alignment with market data. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.


We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact accommodations@illumina.com. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants.

Similar Jobs

Probably Monsters - Senior Publishing Producer

Probably Monsters

Dallas, Texas, United States (On-Site)
4 Months ago
deel. - Talent Acquisition Operations Manager

deel.

United States (Remote)
4 Weeks ago
Boomi  - Talent Strategy Program Manager

Boomi

Vancouver, British Columbia, Canada (Hybrid)
1 Month ago
Jam City - Senior Producer

Jam City

California, United States (Remote)
2 Months ago
Logrhytm - Senior Engineering Manager

Logrhytm

California, United States (On-Site)
1 Month ago
Apple - Engineering Project Manager (SAP Finance)

Apple

Sunnyvale, California, United States (On-Site)
2 Months ago
Next Level Business Services - SAP MM

Next Level Business Services

Naples, Florida, United States (On-Site)
10 Months ago
Roblox - Principal Software Engineer, Real-Time Character Technology

Roblox

San Mateo, California, United States (On-Site)
2 Months ago
Qualcomm - RDK- Lead Engineer

Qualcomm

Chennai, Tamil Nadu, India (On-Site)
2 Months ago
EveryMatrix - LLM Algorithm Engineer

EveryMatrix

Changsha, Hunan, China (On-Site)
4 Months ago

Get notifed when new similar jobs are uploaded

Similar Skill Jobs

Apple - Hardware System Design Engineer

Apple

San Diego, California, United States (On-Site)
2 Months ago
ElevenLabs - Events Manager

ElevenLabs

Spain (Remote)
2 Months ago
HYCU - Product Manager

HYCU

Bengaluru, Karnataka, India (Hybrid)
3 Months ago
bytedance - Optical system engineer - Pico Lab -(AR)- San Jose

bytedance

San Jose, California, United States (On-Site)
10 Months ago
 Many Chat  Inc  - Business Operations Specialist

Many Chat Inc

Barcelona, Catalonia, Spain (Hybrid)
1 Month ago
Guardian - Group Benefits Market Leader, East Region

Guardian

New York, United States (Hybrid)
4 Weeks ago
Shield AI - Senior Staff Product Designer (R3533)

Shield AI

San Diego, California, United States (On-Site)
4 Weeks ago
SoftSwiss - Brand Manager – Senior

SoftSwiss

Warsaw, Masovian Voivodeship, Poland (Remote)
1 Month ago
CME Group - Software Engineer - Fenergo Implementation Specialist

CME Group

Bengaluru, Karnataka, India (On-Site)
3 Months ago
Salesforce - Front End Software Engineer, LMTS: Commerce Cloud - POS CMS

Salesforce

San Francisco, California, United States (On-Site)
1 Month ago

Get notifed when new similar jobs are uploaded

Jobs in San Diego, California, United States

The New York Times - Economy Editor

The New York Times

New York, New York, United States (Hybrid)
3 Months ago
Square - Test Engineer - System Test

Square

Roseville, California, United States (On-Site)
1 Month ago
AECOM - Senior Transportation Engineering Manager

AECOM

Atlanta, Georgia, United States (On-Site)
2 Months ago
Daybreak Game Company LLC - QA Analyst (Temp)

Daybreak Game Company LLC

San Diego, California, United States (On-Site)
1 Year ago
Universal Music - Director, eCommerce & Artist Services

Universal Music

New York, New York, United States (On-Site)
5 Months ago
Alpha Sense - Lead AI Platform Engineer

Alpha Sense

New York, New York, United States (On-Site)
8 Months ago
Hedra - Lead Product Engineer

Hedra

San Francisco, California, United States (On-Site)
4 Months ago
Aera Technology - Business Development Representative

Aera Technology

San Francisco, California, United States (On-Site)
7 Months ago
Opendoor - Home Sales Advisor

Opendoor

Phoenix, Arizona, United States (Hybrid)
1 Month ago
Sawhorse Productions - Senior Roblox Developer

Sawhorse Productions

Los Angeles, California, United States (Remote)
4 Months ago

Get notifed when new similar jobs are uploaded

Software Development & Engineering Jobs

Google - Tech Lead, Software Engineering (For Women in Tech Candidates)

Google

Belo Horizonte, State Of Minas Gerais, Brazil (On-Site)
9 Months ago
bytedance - Software Development Engineer (SDN Traffic Intelligence & Control)

bytedance

San Jose, California, United States (On-Site)
4 Months ago
Qualcomm - ASICS Design Engineer

Qualcomm

Hsinchu City, Taiwan (On-Site)
3 Months ago
Shield AI - Director, Avionics Engineering (R3401)

Shield AI

Dallas, Texas, United States (On-Site)
4 Weeks ago
Whatnot - Software Engineer Intern (Fall 2025)

Whatnot

United States (Remote)
1 Month ago
Wind River - Senior Member of Technical Staff

Wind River

Bengaluru, Karnataka, India (On-Site)
1 Month ago
Capgemini - Principal Software Engineer

Capgemini

Mumbai, Maharashtra, India (On-Site)
3 Months ago
Ambient.ai - Senior Sales Engineer

Ambient.ai

Boston, Massachusetts, United States (Remote)
1 Month ago
Addepar - Staff Software Engineer - Portfolio Experience

Addepar

United States (Remote)
1 Month ago

Get notifed when new similar jobs are uploaded

About The Company

At Illumina, our goal is to apply innovative technologies and revolutionary assays to the analysis of genetic variation and function, making studies possible that were not even imaginable just a few years ago. These studies will help make the realization of personalized medicine possible. With such rapid advances in technology taking place, it is mission critical to have solutions that are not only innovative, but flexible, scalable, and complete with industry-leading support and service. As a global company that places high value on collaborative interactions, rapid delivery of solutions, and prioritizing the needs of its customers, we strive to meet this challenge. Illumina’s innovative, array-based solutions for DNA, RNA, and protein analysis serve as tools for disease research, drug development, and the development of molecular tests in the clinic.



São Paulo, Brazil (Remote)

Bengaluru, Karnataka, India (On-Site)

Singapore, Singapore (On-Site)

Tokyo, Japan (On-Site)

State Of São Paulo, Brazil (On-Site)

Cambridge, England, United Kingdom (Remote)

Singapore, Singapore (On-Site)

Bengaluru, Karnataka, India (Hybrid)

Bengaluru, Karnataka, India (On-Site)

View All Jobs

Get notified when new jobs are added by Illumina

Level Up Your Career in Game Development!

Transform Your Passion into Profession with Our Comprehensive Courses for Aspiring Game Developers.

Job Common Plug