Lead (Staff) Bioinformatics Scientist

undefined ago • All levels • Research Development

Job Summary

Job Description

The Staff Bioinformatics Scientist will work alongside engineering, chemistry and assay teams on R&D projects delivering new sequencing platforms and technologies. This role involves defining bioinformatics milestones, leading data analysis, developing novel tools and pipelines, and contributing to project strategy. The position requires strong bioinformatics and programming skills, initiative, cross-team collaboration, and understanding of product development.
Must have:
  • Represent bioinformatics in R&D projects for novel sequencing products.
  • Lead data quality and bioinformatics function in research or product development.
  • Collaborate with subject matter experts on sequencing technology requirements.
  • Plan and execute strategy for assessing sequencing data quality.
  • Lead analysis, integration, modelling, and interpretation of experimental data.
  • Translate complex analysis results into actionable recommendations.
  • Present results effectively to technical and non-technical stakeholders.
  • Stay current on latest publications and relevant research.
  • Proficient programming skills (Python, R).
  • Strong understanding of next-generation sequencing technologies.
  • Experience with Unix/Linux and High Performance Computing (HPC).
  • Strong data analysis and visualization skills.
  • Proficiency with common bioinformatics algorithms and methods.
  • Hands-on experience with quality control and analysis of various omics data.
Good to have:
  • Experience working with cloud environments (e.g., AWS).
  • Experience with workflow management languages (e.g., Nextflow, WDL).
  • Familiarity with containerization tools (e.g., Docker).
Perks:
  • Deeply rooted in belonging and inclusive environment.
  • Zero-net gap in pay regardless of gender, ethnicity, or race.
  • Employee Resource Groups (ERG) for career development, cultural awareness, and social responsibility.
  • Opportunity to make a difference in human health through genomics.

Job Details

What if the work you did every day could impact the lives of people you know? Or all of humanity?

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

The Staff Bioinformatics Scientist will work alongside engineering, chemistry and assay teams on R&D projects delivering new sequencing platforms and technologies. In this role, the Staff Scientist will represent bioinformatics in cross-functional programs:

  • Defining bioinformatics milestones and requirements · Leading data analysis activities
  • Developing novel tools and pipelines
  • Contributing to project strategy

In addition to strong bioinformatics and programming skills, this position requires a high degree of initiative and cross-team collaboration, as well as a thorough understanding of the product development process.

Responsibilities:

  • Represent bioinformatics in R&D projects across multiple sites for the design, development and validation of novel sequencing products.
  • Lead the data quality and bioinformatics function in a research or product development team, including defining milestones, establishing work priorities, and delegating tasks to other sub-team members as needed.
  • Collaborate with subject matter experts across R&D functions to understand, define, and communicate sequencing technology requirements for research and clinical applications.
  • Contribute to the planning and execution of a comprehensive strategy for assessing quality of data from existing and novel sequencing technologies.
  • Lead the analysis, integration, modelling and interpretation of experimental data. ·
  • Translate complex analysis results into actionable recommendations for technology development and improvement.
  • Present results clearly and effectively to both technical and non-technical stakeholders.
  • Stay current on the latest publications and relevant research and identify established methods that should be incorporate into method development.

Listed responsibilities are an essential, but not exhaustive list, of the usual duties associated with the position. Changes to individual responsibilities may occur due to business needs.

Requirements:

  • Proficient programming skills and experience with several programming languages, such as Python, R, etc.
  • Strong understanding of next-generation sequencing technologies and their underlying principles.
  • Experience working with Unix/Linux and High Performance Computing (HPC) environments.
  • Strong data analysis and visualization skills.
  • Proficiency with common bioinformatics algorithms and methods. Hands on experience of quality control and analysis of data generated from a variety of omics, such as WGS, scRNA, somatic profiling, proteomics, methylation, etc.
  • Excellent communication skills and a proven track record of collaborating with diverse teams.

Desired:

  • Experience working with cloud environments (e.g., AWS).
  • Experience with workflow management languages, such as Nextflow, WDL, etc.
  • Familiarity with containerization tools, such as Docker, and similar technologies.

Education:

Masters/PhD in bioinformatics, computer science, data science, engineering, mathematics or equivalent

We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact accommodations@illumina.com. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.

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About The Company

At Illumina, our goal is to apply innovative technologies and revolutionary assays to the analysis of genetic variation and function, making studies possible that were not even imaginable just a few years ago. These studies will help make the realization of personalized medicine possible. With such rapid advances in technology taking place, it is mission critical to have solutions that are not only innovative, but flexible, scalable, and complete with industry-leading support and service. As a global company that places high value on collaborative interactions, rapid delivery of solutions, and prioritizing the needs of its customers, we strive to meet this challenge. Illumina’s innovative, array-based solutions for DNA, RNA, and protein analysis serve as tools for disease research, drug development, and the development of molecular tests in the clinic.



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