Senior Vice President, Clinical Development & Medical Affairs

Who We Are: 

Click Therapeutics, Inc., develops, validates, and commercializes software as prescription medical treatments for people with unmet medical needs. As a leading innovator of Digital Therapeutics™, Click delivers accessible, clinically proven, FDA-regulated prescription treatments to the smartphone in your hand. Click’s treatments are defined by a commitment to applying technical and scientific rigor and patient-centric design to the development process. This results in uniquely engaging experiences that achieve compelling clinical outcomes for patients seeking new treatment options. Click Therapeutics continuously expands and refines its platform with novel cognitive, behavioral and neuromodulatory mechanisms of action and advanced data-driven tools such as artificial intelligence and machine learning. The digital therapeutics under development on Click’s platform address diverse areas of therapeutic need, including indications in psychiatry, neurology, oncology, immunology, and cardiometabolic diseases. Consistently named a best place to work, Click fosters an inclusive, diverse workforce of innovators, clinicians, scientists, researchers, designers, technologists, engineers and more, united in a common mission to provide patients everywhere access to safe and effective prescription digital therapeutics. For more information, visit www.clicktherapeutics.com and connect with us on LinkedIn. 

About the Role: 

Click is a fully integrated digital therapeutics platform company pioneering two complementary models of innovation: Prescription Digital Therapeutics (PDTs) that are FDA-regulated digital treatments, and Software-Enhanced Drugs (SEDs) in which PDTs augment pharmacologic therapies to personalize and improve clinical outcomes.

As Senior Vice President (SVP), Clinical Development & Medical Affairs, you will be the clinical architect behind both models, leading all internal programs with a relentless focus on automation, operational efficiency, and digital innovation. Reporting to the Chief Medical Officer, you will oversee clinical science, development, operations, and affairs across the entire therapeutic lifecycle—from early discovery through pivotal trials and post-market evidence generation.

You’ll also play a key role externally with pharma collaborators, serving as clinical lead on joint governance committees, shaping and driving strategic co-development and commercialization efforts. This is a rare opportunity to lead within a first-of-its-kind biotech where software and medicine converge, and where clinical development is being redefined for speed, scale, and real-world impact.

This position can be based out of Click’s headquarters located in Tribeca, NYC, at the center of one of the fastest-growing digital health communities or at our industrious office in Boston, MA. We have a hybrid working model that consists of at least 3 days in office each week.

Responsibilities: 

Strategic & Operational Leadership

• Develop and execute a unified clinical R&D strategy across PDTs and SEDs in alignment with corporate and partner goals.
• Drive operational excellence with a focus on automation, streamlined processes, and AI-powered optimization.
• Collaborate with the CMO and executive leadership to shape overall company direction and clinical portfolio strategy.

Clinical Development Execution

• Lead clinical development from concept through registration and beyond, ensuring scientific rigor and compliance with global regulatory standards.
• Oversee a robust clinical operations organization, including trial operations, data science, biostatistics, and medical writing.
• Implement technology-forward systems to enhance trial efficiency, data quality, and decision-making.

Medical Affairs Leadership

• Build and lead a strategic medical affairs function supporting scientific communication, stakeholder engagement, scientific communications, and health economics and outcomes research (HEOR).
• Translate clinical insights into impactful product development, access strategies, and commercial execution.

Cross-Functional & External Collaboration

• Partner closely with product, engineering, data, regulatory, quality, commercial, and legal teams for seamless development and lifecycle execution.
• Represent Click on joint governance boards with global pharma partners, ensuring coordinated execution of co-developed assets and alignment on clinical milestones.
• Contribute to alliance management and business development activities to expand Click’s innovation and partnership pipeline.

People & Culture

• Recruit, mentor, and develop top-tier scientific and clinical talent.
• Foster a culture of innovation, accountability, inclusion, and excellence across the organization.

Required Qualifications

• MD or MD/PhD with clinical and scientific background preferably in neurology, neuroscience, psychiatry, behavioral health, or related CNS discipline.
• 15+ years of progressive clinical R&D leadership in biotech, pharma, or digital health.
• Proven track record of advancing biopharmaceuticals and/or medical devices through development, regulatory approval, and commercialization.
• Demonstrated ability to optimize clinical operations via automation, AI, and technology-enabled processes.
• Experience with cross-functional leadership and regulatory strategy.
• Expertise with real-world evidence generation, digital endpoints, and decentralized clinical trial models.
• Strong communication and leadership skills with the ability to operate at executive and governance levels.

Preferred Qualifications: 

• Expertise in digital interventions (software as a medical device, SaMD) including regulatory pathways and clinical validation strategies.
• Experience with biotech/pharma partnerships and serving on joint governance boards.

Compensation:

The base salary range for this position is between: $300,000 - $350,000. The final base salary will be dependent upon skills, experience and location. In addition to the base salary, Click Therapeutics offers an annual performance-based cash bonus and a generous equity package.

Benefits: 

The role includes great benefits and is an excellent wealth-building opportunity at a fast-growing pre-IPO company in a nascent and extremely exciting space. 

Competitive Salary with Annual Review | Cash Bonus | Stock Options | 5% 401(k) matching | Medical | Dental | Vision | Life Insurance | Voluntary Benefits | Unlimited PTO | Uber One | Nectar Rewards | One Medical | Fertility Support | Fitness Reimbursement | Bike Membership | Professional Development Stipend | DoorDash and Catered Lunches | Parent Benefits | LinkedIn Learning | Gemini Enterprise Stack | Industrious Workspaces | Commuter Subsidies | Flexible Work Arrangement | Choice of Mac or Windows | Sponsored Company Events | Office Snacks and Beverages | Much More…

Equal Employment Opportunity: 

Click Therapeutics is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Click Therapeutics also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Click Therapeutics in the U.S. In certain circumstances it may be advantageous to Click Therapeutics to support the application(s) for temporary visa classification and/or sponsor applications for permanent residence so that a foreign national colleague can accept or remain in a work assignment in the U. S. For certain classes of temporary visas, the resulting work authorization may be specific to Click Therapeutics and the specific job and/or work site. Click Therapeutics may at its business discretion decide to or refrain from obtaining, maintaining

and/or extending the temporary visa status and/or sponsoring a colleague for permanent residency and /or employment eligibility, considering factors such as availability of qualified U.S. workers and the colleague's long-term prospects for securing lawful permanent residence, among other reasons. Employment applicants requiring immigration sponsorship must disclose, when initial application for employment is made, whether or not they are legally authorized to work for Click Therapeutics in the U.S. and, if so, whether that authorization permits them to work in the job they seek. In no case should Click Therapeutics support of a colleague's temporary visa application or sponsorship of a colleague for permanent residence be construed to guarantee success of that application or amend or otherwise invalidate the "at-will" employment relationship between the colleague and Click Therapeutics. 

Recruitment Phishing Scams: 

Fake job advertisements and offers are increasingly appearing on the internet. If you have encountered a job posting or have been approached with a job offer that you suspect may be fraudulent, we strongly recommend you do not respond and report it to the Federal Trade Commission and the FBI at https://www.ic3.gov/Home/ComplaintChoice.

Please be mindful of the following:

• Click Therapeutics will only reach out to you through an “@clicktherapeutics.com” email address.

• Other than your email address or telephone number, which you may provide via a job application portal, Click Therapeutics will never ask you to provide personally identifiable information about yourself (such as a Social Security Number or Driver’s License Number) via a messaging application (like that used on the LinkedIn platform or Microsoft Teams).

• Click Therapeutics will conduct interviews face-to-face over Zoom.

• All job postings will be listed on the Click Therapeutics official career page.