Staff Bioinformatics Scientist – Multi-omics Technical Lead

1 Year ago • 3-6 Years • Research Development

Job Summary

Job Description

The Staff Bioinformatics Scientist will develop novel algorithms and bioinformatics methods to extract biological meaning from Illumina’s multi-omic product portfolio. They will design and implement solutions in the form of model design and software, collaborating within a team. Responsibilities include defining requirements, assessing accuracy, streamlining customer experience, enabling end-user applications, and proposing research directions. The ideal candidate will possess strong bioinformatics and programming skills, initiative, cross-functional collaboration abilities, and a thorough understanding of the product development process. This role involves algorithm design, implementation in C++ software, representing bioinformatics in a product development team, defining strategy, staying current on publications, and mentoring peers.
Must have:
  • Expertise in genomics and multi-omic data analysis.
  • Expertise in NGS secondary analysis algorithms.
  • Expertise in C++/C high-performance software development.
Good to have:
  • Experience with Multiomics assays (epigenetics, methylation, scRNA).
  • Familiarity with collaboration and product development tools.
  • Familiarity with next-generation sequencing technologies.
Perks:
  • Flexible time off
  • Private medical insurance
  • Compassion and care time off
  • Leisure travel insurance
  • Pension
  • Employee stock purchasing program
  • Volunteer time off

Job Details

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. Staff Bioinformatics Scientist – Multi-omics Technical Lead Cambridge - Onsite/Hub and Hybrid or Europe remote We have an exciting new opportunity for a Staff Bioinformatics Scientist to join our Multiomics Bioinformatics organization and will support the development of Illumina’s portfolio of multiomic assays, library preps, and associated software. Why Us Illumina's employee benefits are industry-leading and include flexible time off, private medical insurance, compassion and care time off, leisure travel insurance, pension, employee stock purchasing program, volunteer time off, and much more! The Role The Multiomics Bioinformatics organization supports products spanning epigenetics, transcriptomics, and proteomics. The Staff Bioinformatics Scientist will be responsible for developing novel algorithms and bioinformatics methods to extract biological meaning from Illumina’s growing multi-omic product portfolio. They will be responsible for designing and implementing solutions in the form of model design and software as well as collaborating with others to do so in a team-focused workflow. They will be responsible for helping to define and drive the success of the complete product, including defining requirements, assessing accuracy, streamlining customer experience, enabling end-user applications and proposing novel research directions. They will have a strong background in computer science, algorithms, statistics, and/or digital signal processing in addition to expertise in genomics, next generation sequencing, and a broad ecosystem of related assays and biotechnologies. The ideal candidate will have a track record of both innovative and pragmatic bioinformatics methods development and delivery. In addition to strong bioinformatics and programming skills, this position requires a high degree of initiative and cross-functional collaboration, as well as a thorough understanding of the product development process. Responsibilities:
  • Design, prototype and implement innovative computational and/or statistical algorithms to extract meaningful biological signal from multi-omic assays.
  • Implement algorithms in production-grade C++ software.
  • Represent bioinformatics in a product development team, establish work priorities and communicate / delegate tasks to other sub-team members as needed.
  • Work cross-functionally with leaders from product management, assay development, and software engineering to define strategy and roadmap for multiomics methods and customer facing software
  • Stay current on latest publications and relevant research and identify established methods that should be incorporated into method development.
  • Submit invention disclosures or innovative ideas for technology, processes and products 
  • Mentor peers and supporting scientists, engineers on technical skills in one's area of expertise 
Listed responsibilities are an essential, but not exhaustive list, of the usual duties associated with the position. Changes to individual responsibilities may occur due to business needs. Key skill requirements:
  • Expertise in genomics and experience with analyzing error modes and actionable signal in multi-omic data sets
  • Expertise in algorithms for NGS secondary analysis: Mapping-Alignment and Variant Calling
  • Expertise in high-performance software development using C++/C or similar languages
  • Experience with Unix/Linux environments, including shell scripting and High Performance Computing (HPC) cluster usage
  • Familiarity with common bioinformatics pipelines and data formats
  • Solid understanding of statistical and biological concepts
Desired experience:
  • Experience with Multiomics assays including: epigenetics, methylation, or scRNA
  • Familiarity with collaboration and product development tools (confluence, JIRA, JAMA)
  • Familiarity with next-generation sequencing technologies
  • Strong communication skills and a history of collaboration with teams from diverse background
Education requirements: Masters/PhD in bioinformatics, computer science, data science, engineering, mathematics or equivalent Typically requires a minimum of 6 years of related experience with a Master’s degree; or a PhD with 3+ years of experience; or equivalent experience Illumina believes that everyone has the ability to make an impact, and we are proud to be an equal opportunities employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information.

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About The Company

At Illumina, our goal is to apply innovative technologies and revolutionary assays to the analysis of genetic variation and function, making studies possible that were not even imaginable just a few years ago. These studies will help make the realization of personalized medicine possible. With such rapid advances in technology taking place, it is mission critical to have solutions that are not only innovative, but flexible, scalable, and complete with industry-leading support and service. As a global company that places high value on collaborative interactions, rapid delivery of solutions, and prioritizing the needs of its customers, we strive to meet this challenge. Illumina’s innovative, array-based solutions for DNA, RNA, and protein analysis serve as tools for disease research, drug development, and the development of molecular tests in the clinic.



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